Numbering Code	U-ENG27 37129 LJ61	Year/Term	2022 ・ Second semester
Number of Credits	2	Course Type	Lecture
Target Year		Target Student
Language	Japanese	Day/Period	Thu.2
Instructor name	TABATA YASUHIKO (Institute for Life and Medical Sciences Professor) EIRAKU GENJI (Institute for Life and Medical Sciences Professor) OHGUSHI MASATOSHI (Institute for Life and Medical Sciences Associate Professor)
Outline and Purpose of the Course	It is important in the field of life science to understand biochemistry and biological medicine in terms of organic material chemistry. The way to think and view the biological system and bioprocess at the molecular level can make clear the academic knowledge of life science and contribute to the development of engineering-medicine-pharmacy interdisciplinary research area. In this lecture, proteins, polysaccharides, and lipids of bio-related substances as well as cells, cell membrane, extracellular matrix of biological system are explained in terms of chemical biology. As a representative of engineering-medicine-pharmacy interdisciplinary research area, drug delivery system (DDS) and regenerative medicine are introduced. In addition, some topics in the field of life science, including stem cells, body defense and immunology, and endocrine disruptor, are also covered.
Course Goals	The objective of the lecture is to obtain the fundamental knowledge of proteins, polysaccharides, lipids, cells, and extracellular matrix and understand stem cells, body defense, DDS, regenerative medicine, and endocrine disruptor of life science application.
Schedule and Contents	Proteins and enzymes,2times,Structure and function of proteins and enzymes Polysaccharides and lipids,1time,Structure and function of polysaccharides and lipids Cell and cell membrane,1time,Structure and function of cells and membrane transportation Signal transduction,1time,Signal transduction at cell membrane Energy conversion,1time,Oxidative phosphorylation to generate ATP Cytoskeleton,1time,Cellular biomechanics and biochemistry of cytoskeleton Body defense and immunology,1time,System and function of body defense and immunology Stem cells,1time,System, function, and medical application of stem cells Cell and extracellular matrix,1time,Structure and function of extracellular matrix Regenerative medicine and material science,2times,Overview of regenerative medicine based on material science Drug delivery system (DDS),1time,Overview of DDS based on material science Endocrine disruptor,1time,Overview of endocrine disruptor based on material science Achievement evaluation,1time,Credit evaluation based on the understanding level of lecture contents
Evaluation Methods and Policy	The credit is judged by the scheduled examination and the attendant rate.
Course Requirements	None
References, etc.	Fundamentals of Biochemistry: Life at the Molecular Level；Wiley isbn{}{9780470547847}、 Molecular biology of the Cell ；Garland Science isbn{}{9780815344322}、 ますます重要になる細胞周辺環境（細胞ニッチ）の最新科学技術；株式会社メディカルドゥ isbn{}{9784944157846}、 Immunology；Saunders isbn{}{9780323080583}、 生物薬剤学；株式会社南江堂 isbn{}{9784524403059}、 絵で見てわかるナノDDS；株式会社メディカルドゥ isbn{}{9784944157884}
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