Introduction to Biochemistry-E2

Numbering Code U-LAS14 20037 LE68 Year/Term 2022 ・ Second semester
Number of Credits 2 Course Type Lecture
Target Year Mainly 1st & 2nd year students Target Student For science students
Language English Day/Period Tue.3
Instructor name Marco,Marques Candeias (Graduate School of Medicine Senior Lecturer)
Outline and Purpose of the Course This introductory course focuses on the basic concepts of biochemistry. It begins from the molecular design of life and considers its major players; DNA as the genetic material, and then RNA, proteins, carbohydrates and lipids. Based on these preliminary concepts, the course then continues to consider the basic processes involved in metabolism and energy generation in living organisms.
Course Goals To appreciate that by understanding some of the underlying concepts and principles of the molecular and biochemical processes that control life, we can more easily comprehend the complexities of diverse biological and physiological systems.
Schedule and Contents Main Topics:
1. Introduction to biochemistry, an evolving science
2. Genomes, DNA and DNA replication
3. Genes and gene expression
4. RNA: Life's Indispensable Molecule
5. Protein composition and structure
6. Exploring DNA and RNA
7. Exploring proteins
8. Introduction to enzymes
9. Carbohydrates
10. Lipids and cell membranes
11. Introduction to metabolism
12. Glycolysis
13. Citric acid cycle
14. Oxidative phosphorylation
15. Final examination
16. Feedback discussions

(the above subjects will be taught in 14 classes + examination + feedback)
Evaluation Methods and Policy Evaluation will be based on class attendance and active participation (~20 %), mid-course tests (~30 %) and a final examination (~50 %)
Course Requirements None
Study outside of Class (preparation and review) *Full lecture slides and additional original video clips will be provided before each lecture. It is expected that students will have read and watched through the slides and clips at least once before each lecture to familiarize themselves with the contents. During the lecture, active discussion and participation (e.g. by a series of Q&A) will ensure a greater understanding of the basic concepts. Finally, a private review of the slides immediately after the lecture will ensure a full and solid understanding of the lecture concepts.
*The course is associated with a series of small-group, weekly seminars that will help students obtain a deeper understanding of the basic concepts
Textbooks Textbooks/References Molecular Biology of the Cell, Alberts; Walter; etc, (Garland Science), ISBN:978-0815344537
Biochemistry (Lippincott's Illustrated Reviews Series), Denise R. Ferrier, (Lippincott Williams & Wilkins), ISBN:978-1496344496
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