京都大学 京都大学

Introduction to Immunology-E2 :The body's defense system

Numbering Code U-LAS14 20072 LE68 Year/Term 2022 ・ Second semester
Number of Credits 2 Course Type Lecture
Target Year Mainly 1st & 2nd year students Target Student For all majors
Language English Day/Period Thu.3
Instructor name KIM MINSOO (Graduate School of Medicine Associate Professor)
Outline and Purpose of the Course Our body is constantly exposed to foreign microbes, many of which cause infectious diseases. However, our body has an intricate immune system that defends against such infections. Understanding this host immune system gives us greater insights into human diseases and enables us to develop novel therapeutic tools. This course, therefore, focuses on the immune system at the molecular, cellular, and whole-organism levels. Topics include: cells and tissues of the immune system, lymphocyte development, structure and function of antigens and antibodies, cell biology of antigen processing and presentation, pathogenesis of immunologically-mediated diseases, and disease control. The first four lectures provide a simple introduction to immunology, and subsequent lectures focus on specialized topics that will give a detailed understanding of the immune system.
Course Goals To understand the basic concepts of immune cells and organs.
To understand how our body responds to foreign antigens and self-derived threats.
To become familiar with various research topics in immunology.
Schedule and Contents 1. Introduction to immunology: the body’s defense
2. Elements of the immune system and their roles in defense
3. Introduction to innate immunity: the first lines of defense
4. Overview of adaptive immunity
5. Cells and tissues of the immune system
6. Antibodies and antigens
7. Inflammation and tissue repair
8. Recognition of self and non-self by the innate immune system
9. B cell development and antibody mediated immunity
10. Antigen presentation by T lymphocytes
11. Immunological memory and vaccination
12. Failures of the body’s defenses-Immunodeficiency
13. Disorders in the immune system-Autoimmunity, Allergy
14. Immunity to Tumors
15. Final examination
16. Feedback
Evaluation Methods and Policy Evaluation will be based on class attendance and participation (40%), homework (20%), and Final exam (40%).
Course Requirements The course is open to all students, although a background in cell biology is highly recommended.
Study outside of Class (preparation and review) To achieve the course goals, students read the recommended textbooks before the class and review the course handouts.
Textbooks Textbooks/References Cellular and Molecular immunology 10th edition, Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai, ( Elsevier,2022), ISBN:9780323757485
Janeway’s Immunology, Kenneth Murphy et al., (WW Norton), ISBN:9780393884890
References, etc. Kuby Immunology, Jenni Punt et al., (WH Freeman), ISBN:978-1319114701
The Immune System 5th edition, Peter Parham, (WW Norton), ISBN:978-0-393-53335-4
Molecular Biology of the Cell, Bruce Alberts et al., (WW Norton), ISBN:978-0815344643
Introduced during class
PAGE TOP