ILAS Seminar-E2 :How to make scientific Breakthrough- Learning from Nobel discoveries

Numbering Code U-LAS70 10002 SE50 Year/Term 2022 ・ Second semester
Number of Credits 2 Course Type seminar
Target Year Mainly 1st year students Target Student For all majors
Language English Day/Period Fri.5
Instructor name KIM MINSOO (Graduate School of Medicine Associate Professor)
Outline and Purpose of the Course Since 1901, the Nobel Prize has served as an acknowledgement of major contributions to the life sciences. In this ILAS seminar, we will focus on several contributions to the fields of Medicine/Physiology and Chemistry that have been recognized by the Nobel Prize. The course will begin with two classes that review the philosophy and sociology of such scientific discoveries. Subsequent classes will shift to an exploration of the application of these theories to specific cases. By studying the work and careers of laureates, students will become familiar with the philosophies and methods that have led to great breakthroughs in twentieth-century science. The course will end with a discussion of the future prospects of medical innovations. Although life science is the main focus, the study of relevant Nobel prizes in physics or peace is also possible. During the course, students will practice to reading research papers and actively participate in group discussions.
Course Goals To understand the philosophy and methodology of the Nobel laureates
To gain basic knowledge of the life sciences and biotechnology
To improve critical thinking skills and the discussion and presentation of scientific topics
Schedule and Contents Week 1. Introduction of course: Nobel lecture
Week 2. History of scientific discoveries
Week 3-6. Nobel stories of “Gene to Cell”: Chromosome, Reverse Transcription, Protein folding, Protein degradation, cell division
Week 7. Student practice: Let's make a "3D-DNA model"
Week 8. Novel biotechnology in medicine: RNA interference, polymerase chain reaction, green fluorescent protein
Week 9. Student practice: Reading Nobel papers
Week 10-13. Discovery of the causes of diseases (and therapies): tuberculosis (and streptomycin), malaria, cancer, immune cells, and immune therapy
Week 14. Innovations in medical sciences: What is the next innovation?
Week 15. Student presentations on selected Nobel prizes
Week 16. Feedback
Evaluation Methods and Policy Evaluation will be based on class attendance and participation (60%) and a final presentation (40%).
Course Requirements None
Study outside of Class (preparation and review) To achieve the course goals students review the course handouts.
References, etc. Molecular Biology of the Cell, Bruce Alberts et al., , ISBN:978-0815344643
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