Introduction to Genetics and Evolution-E2

Numbering Code U-LAS14 20034 LE68 Year/Term 2022 ・ Second semester
Number of Credits 2 Course Type Lecture
Target Year Mainly 1st & 2nd year students Target Student For science students
Language English Day/Period Mon.3
Instructor name GUY, Adam Tsuda (Graduate School of Biostudies Associate Professor)
Outline and Purpose of the Course This course will provide an introduction to genetics and evolution, starting with the most fundamental topics. What are chromosomes? What is the genetic code? What is natural selection? We will begin by learning some of the basics about DNA, the genetic material: the Central Dogma, concepts of dominant and recessive modes of inheritance, mitosis and meiosis, and then we will progress to more specific topics such as human genetic diseases and genetic engineering. We will then move on to some basic concepts of evolutionary biology, such as common descent, genetic variation, abiogenesis and reproductive success. This course will introduce students to the simultaneous unity and diversity of living things.
Course Goals Students will become familiar with molecular biology, classical genetics, gene mutations, genetic diseases, genetic engineering and genetically modified organisms, and learn some basic principles of evolution including natural selection, gene mutation and adaptation.
Schedule and Contents 1. Introduction
2. The Structure of DNA and Chromosomes
3. RNA
4. Gene Expression
5. Mitosis and Meiosis
6. Genetic Variation
7. Model Organism for the Study of Genetics
8. Cancer and Genetic Diseases in Humans
9. Genetic Engineering and Gene Therapy
10. Introduction to Evolutionary Biology
11. The Tree of Life: Classification and Phylogeny
12. Genes and Evolution
13. A Brief History of Life on Earth
14. Evolution, Science and Society
15. Final Exam
16. Feedback Class
Evaluation Methods and Policy Lectures will encourage student participation. There will be a final exam and some mini-quizzes to assess comprehension. Evaluation: attendance and student participation: 40%; quizzes: 30%; final exam: 30%.
Course Requirements This is an introductory course. There are no requirements but knowledge of basic biology is highly recommended. The course will be taught in English. Some students may have some knowledge of biology but maybe not in English language. Other students may have good English skills, but will have to learn some technical terms used in the study of genetics and evolution.
Study outside of Class (preparation and review) Students may need 2-3 hours per week to review the lecture material and look up any background information as necessary. Some students may know the subject already, but need to learn the English vocabulary; others may need to learn both Biology and English.
Textbooks Textbooks/References Lecture handouts will be provided for each class.
References, etc. Essential Genetics and Genomics 7th edition, Hartl, (Jones and Bartlett Learning), ISBN:9781284152456, Most of the content of this course is covered in this textbook.
The Molecular Biology of the Cell, Alberts, Johnson, Lewis, Morgan, Raff, Robert & Walter, (Norton), ISBN:9780815344322
Campbell Biology, Wasserman, Minorsky, Cain, Urry, Waterman, Stanley & Reece, (Pearson), ISBN:9780134082318
Evolution, Futuyma & Kirkpatrick, (Sinauer), ISBN:9781605356051
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