Advanced Organic Chemistry
| Numbering Code |
G-ENG16 5H818 LJ60 G-ENG15 6H818 LJ60 G-ENG13 6H818 LJ60 |
Year/Term | 2022 ・ First semester | |
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| Number of Credits | 1.5 | Course Type | Lecture | |
| Target Year | Target Student | |||
| Language | Japanese | Day/Period | Tue.1 | |
| Instructor name |
OOE KOUICHI (Graduate School of Engineering Professor) HIROSE TAKASHI (Institute for Chemical Research Associate Professor) NAGAKI AIICHIROU (Graduate School of Engineering Associate Professor) KIMURA YUU (Graduate School of Engineering Associate Professor) |
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| Outline and Purpose of the Course | To acquire basic concepts and principles of organic chemistry; to understand different reactions, from basic to cutting-edge, and the syntheses based on them; to propose synthetic routes for given target organic compounds; and to make related presentations. Develop the ability of total organic synthesis through discussions. | |||
| Course Goals | Understand basic concepts and principles of organic chemistry and acquire the ability to think of synthetic routes for relatively complex organic compounds based on them. | |||
| Schedule and Contents |
Chemoselectivity (2 sessions) Introduction and chemoselectivity Regioselectivity (2 sessions) Controlled Aldol Reactions Stereoselectivity (2 sessions) Stereoselective Aldol Rections Strategies (2 sessions) Alternative Strategies for Enone Synthesis Choosing a Strategy (2 sessions) The Synthesis of Cyclopentenones Summary (2 sessions) Proposal and Presentation regarding Total Synthesis of Target Molecules |
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| Evaluation Methods and Policy |
Comprehensive evaluation by quizzes of each unit and investigation / presentation of the total synthetic route of target compound. Grades are evaluated based on raw scores of the overall evaluation |
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| Course Requirements | Students should have a good understanding of undergraduate organic chemistry. | |||
| Study outside of Class (preparation and review) | Students should briefly glance over the handouts and textbook, and prepare for the contents of each unit before attending any lecture. In addition, students will deepen their understanding of the contents of each unit based on quiz tasks assigned in each lecture and their reviews. It is advisable for students to devote twice the time spent in teaching sessions to prepare for and review these sessions. In addition, students must devote sufficient time to investigation of the total synthetic route of the target compound given as a task, preparation of its proposal, and preparation for an oral presentation. | |||
| Textbooks | Textbooks/References | Paul Wyatt, Stuart Warren "Organic Synthesis. Strategy and Control" (Wiley) ISBN: 978-0-471-92963-5 | ||
| References, etc. | Others | |||
