Introduction to Physical Chemistry for Drug Discovery
| Numbering Code | G-PHA01 51217 LJ86 | Year/Term | 2022 ・ Irregular, First semester | |
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| Number of Credits | 2 | Course Type | Lecture | |
| Target Year | 1st and 2nd year master's students | Target Student | ||
| Language | Japanese | Day/Period | ||
| Instructor name |
KATOU HIROAKI (Graduate School of Pharmaceutical Sciences Professor) ISHIHAMA YASUSHI (Graduate School of Pharmaceutical Sciences Professor) ONO MASAHIRO (Graduate School of Pharmaceutical Sciences Professor) TAKAKURA YOSHINOBU (Graduate School of Pharmaceutical Sciences Professor) MATSUZAKI KATSUMI (Graduate School of Pharmaceutical Sciences Professor) HOSHINO MASARU (Graduate School of Pharmaceutical Sciences Associate Professor) SUGIYAMA NAOYUKI (Graduate School of Pharmaceutical Sciences Associate Professor) Hiroyuki Watanabe (Graduate School of Pharmaceutical Sciences Senior Lecturer) OGAWA HARUO (Graduate School of Pharmaceutical Sciences Associate Professor) KAWANO KENICHI (Graduate School of Pharmaceutical Sciences Assistant Professor) |
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| Outline and Purpose of the Course | This course offers introductory lectures to students majoring in physical chemistry-related pharmaceutical sciences in the master's program. It aims to develop students' understanding of cutting-edge research in fields that are important when taking a physical chemistry approach to life sciences which is the basis of drug discovery, including spectroscopy, thermodynamics, mass spectrometry, structural biology, reaction kinetics, and analytical chemistry. It also aims to equip students with the basic understanding needed to work independently. To that end, the course will teach students about the fundamentals of each field, using examples of their application in actual scientific research. | |||
| Course Goals |
(1) To gain a graduate school-level understanding of the main fields of physical chemistry in pharmaceutical sciences, namely mass spectrometry, spectroscopy, thermodynamics, structural biology, and the analytical chemistry of organisms. (2) To learn about and understand examples of pioneering research and the latest trends in physical chemistry in pharmaceutical sciences. (3) To develop the ability to independently research, understand, and consider pioneering research from physical chemistry in pharmaceutical sciences. |
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| Schedule and Contents |
(1) Introductory lectures (2)-(5) Principles and applications of the latest in mass spectrometry (6)-(8) Principles, techniques, and application examples of the latest in structural biology (9)-(11) Data gathering and analysis of the latest in spectroscopy and thermodynamics, and their applications (12)-(14) Principles of the latest in molecular imaging and its application in bioanalysis (15) Discussion |
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| Evaluation Methods and Policy |
Students will be evaluated based on their proactive input (e.g., their remarks, questions, and answers) in lectures (20%) and on subject reports assigned based on class content (80%). Credits will not be given if a student misses 25% or more of classes. All reports must be submitted. High marks will be given to reports demonstrating original thinking. |
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| Course Requirements | None | |||
| Study outside of Class (preparation and review) | Students should read references and academic papers about what they learn in lectures to improve their understanding. For subjects that are directly relevant to their own research, students should undertake specific study and examination of the applications in research, and are encouraged to engage in enthusiastic discussion with lecturers and research supervisors. | |||
| Textbooks | Textbooks/References | Not used | ||
| References, etc. | David W. Mount. Bioinformatics, Medical Science International, ISBN:489592307X. Yoneda, Y., Seimei Kagaku kara Souyaku he no Inobeeshon, (Nanzando) ISBN:ISBN978-4-525-13451-8. Hirokawa, T., Web de Jissen Seibutsugaku Jouhou Riterashii, (Nakayama Shoten) | |||
