Skill Development for Target Discovery
| Numbering Code | G-PHA02 75101 PJ86 | Year/Term | 2022 ・ Irregular, year-round | |
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| Number of Credits | 4 | Course Type | Practical training | |
| Target Year | 1st and 2nd year master's students | Target Student | ||
| Language | Japanese | Day/Period | ||
| Instructor name | HIRASAWA AKIRA (Graduate School of Pharmaceutical Sciences Associate Professor) | |||
| Outline and Purpose of the Course |
In this course, students gain practical knowledge of the experiment skills they need to search for and identify target genes in drug discovery, including gene discovery analysis experiments and genetic engineering experiments. Students will acquire experiment skills to identify the genes (target genes for pharmaceutical treatment) that cause disease. They will also acquire experiment skills to assess whether the genes responsible for a specified disease are the direct cause of that disease or whether it might be optimal as a target gene for drug development. |
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| Course Goals | Upon understanding the underlying genome research and informatics, to learn experimental methods for searching for target genes. | |||
| Schedule and Contents |
Syllabus 1-15: The following practical training will be held: ・Introduction to genomic drug discovery ・Genome research and genomic drug discovery ・Target molecule hunting in drug discovery ・Validation of target molecules in drug discovery ・Genomic drug discovery sciences and pharmacogenomics ・Genomic drug discovery sciences and transcriptome analysis ・Status and prospects of transcriptome analysis ・Genomic drug discovery science and proteome analysis ・Status and prospects of proteome analysis ・Genomic drug discovery sciences and metabolome analysis ・Status and prospects of metabolome analysis ・Pharmacoinformatics research ・Forefront of genomic drug discovery and protein kinase ・Forefront of genomic drug discovery and the search for orphan receptor ligands ・Discussion |
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| Evaluation Methods and Policy | Students will be comprehensively evaluated based on lecture attendance and topic reports. | |||
| Course Requirements | None | |||
| Study outside of Class (preparation and review) | Students should independently study and read papers related to the research discussed in class, as this will help them deepen their understanding. | |||
| Textbooks | Textbooks/References | Not used; printouts will be distributed where appropriate. | ||
| References, etc. | Others; may be specified according to class content. | |||
