Laboratory Practice in Basic Pharmacodynanic Sciences

Numbering Code G-PHA01 74208 PJ86 Year/Term 2022 ・ Irregular, year-round
Number of Credits 1 Course Type Practical training
Target Year 1st and 2nd year master's students Target Student
Language Japanese Day/Period
Instructor name ONO MASAHIRO (Graduate School of Pharmaceutical Sciences Professor)
TAKAKURA YOSHINOBU (Graduate School of Pharmaceutical Sciences Professor)
KANEKO SHIYUUJI (Graduate School of Pharmaceutical Sciences Professor)
TAKAHASHI YUUKI (Graduate School of Pharmaceutical Sciences Associate Professor)
SHIRAKAWA HISASHI (Graduate School of Pharmaceutical Sciences Associate Professor)
Hiroyuki Watanabe (Graduate School of Pharmaceutical Sciences Senior Lecturer)
Outline and Purpose of the Course (Aim) This course aims to teach students basic experiment methods and approaches in molecular imaging, pathofunction bioanalysis, pharmacokinetics, and central and peripheral pharmacology, and also aims to equip them with experiment planning skills and teaching methods.
(Summary) In this course, students will provide instruction in practical training in the fields of radiochemistry, clinical analytical chemistry, pharmaceutical sciences, and pharmacology in Specialized Training for Pharmacy 4 to pharmaceutical sciences undergraduates.
Course Goals ・To learn basic experiment methods and approaches in one's area of specialized research, and to learn experiment planning skills and teaching methods.
・To develop presentation and communication skills by directly leading pharmaceutical sciences undergraduates.
Schedule and Contents 1-15: The following practical training will be held:
Design and planning of practical training
 Design practical training and plan experiments relating to radiochemistry, clinical analytical chemistry, pharmaceutical sciences, and pharmacology
Preparation and preliminary experiments
Prepare practical training content relating to radiochemistry, clinical analytical chemistry, pharmaceutical sciences, and pharmacology to explain to undergraduate students, and carry out preliminary experiments to assess the validity of experiment plans
Instruction in practical training
・Experiments on the safe handling and management of radiation and radioactive substances
・Experiments and analytical exercises on radiation measurement
・Experiments on the preparation of radioactive pharmaceuticals
・Experiments and analytical exercises on radioactive biomolecular imaging
・Experiments on photobiomolecular imaging
・Experiments and analytical exercises on quantitative measurements of biologically active substances and drugs
・Experiments and analytical exercises on the safety of pharmaceuticals
・Experiments and mechanism analysis of the gastrointestinal absorption of drugs using rats
・Pharmacokinetic analysis based on animal experiment data
・Clearance theory-based pharmacodynamic simulation
・Experiments and analysis of the disintegration and dissolution of solid preparations for internal use
・Drug efficacy analysis of cardiovascular and gastrointestinal action drugs using rats and biopsy specimens
・Drug efficacy analysis of analgesics and central nervous system agents using mice
・Double-blind drug efficacy analysis of caffeine and related drugs on human work capacity
Presentations and discussion of practical training results
Presentations and discussion of practical training results relating to radiochemistry, clinical analytical chemistry, pharmaceutical sciences, and pharmacology
Evaluation Methods and Policy Students will be comprehensively evaluated based on practical training attendance, development and planning of practical training, preparation and preliminary experiments, and the quality and appropriateness of their instruction in practical training.
Course Requirements None
Study outside of Class (preparation and review) ・Students should carry out sufficient advance preparation before commencing practical training. After the practical training, students should fully consider the experiment results and verify the presentations and leadership methods.
Textbooks Textbooks/References Practical training in pharmacy
References, etc. Others; printouts will be distributed where appropriate.
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