Research in Basic Pharmacology and Drug Delivery

Numbering Code G-PHA01 73207 EJ86 Year/Term 2022 ・ Irregular, year-round
Number of Credits 4 Course Type Experiment
Target Year 1st and 2nd year master's students Target Student
Language Japanese Day/Period
Instructor name YAMASHITA FUMIYOSHI (Graduate School of Pharmaceutical Sciences Professor)
HIGUCHI YURIKO (Graduate School of Pharmaceutical Sciences Associate Professor)
Outline and Purpose of the Course (Aim) By conducting research in the fields of advanced drug delivery and pharmacology, this course aims to teach students how to approach research and draft research plans, as well as experimental techniques, data sorting methods, and problem-solving skills.
(Summary) Research on the development and assessment of drug delivery systems, including nucleic acid drugs, protein pharmaceuticals and cellular pharmaceuticals, as well as in vivo kinetics and safety pharmacology.
Course Goals Students will conduct research in the fields of drug delivery and pharmacology, learning how to approach research and draft research plans, as well as learning experiment techniques, data sorting methods, and developing their problem-solving skills.
Schedule and Contents 1-15: The following experiments will be conducted:
・Experiments on the development and evaluation of delivery systems for nucleic acid drugs
・Experiments on the development and evaluation of delivery systems for biologically active proteins
・Experiments on the development and evaluation of cell therapy
・Experiments on the development and evaluation of bio-imaging technology
・Experiments on the development and evaluation of macromolecular prodrugs
・Experiments on functional molecules and particle discovery as DDS materials
・Experiments on the development and evaluation of MEMS for drug delivery
・The development of new experiment methods to evaluate whole-body and cellular pharmacokinetics
・Experiments on the development of pharmacokinetic modeling and simulations
・Experiments on clinical pharmacokinetic analysis
・Experiments on pharmacokinetics and safety evaluation using MEMS technology
・Experiments on functional assessments of drug transporters
・Experiments on medical big data analysis
・Experiments on the side effect mechanisms of cancer drugs
Evaluation Methods and Policy Students will be comprehensively evaluated based on their ability to draft and carry out research, as well as their attitude.
Course Requirements None
Study outside of Class (preparation and review) It is important that students do not neglect the study and preliminary research needed to carry out research.
Textbooks Textbooks/References Not used; necessary materials and information will be provided as needed. Students should get in touch if they have any doubts or require guidance.
References, etc. Others; use original articles, review articles, and books where appropriate.
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