Research in Basic Medicinal and Organic Chemistry
| Numbering Code | G-PHA01 73201 EJ86 | Year/Term | 2022 ・ Irregular, year-round | |
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| Number of Credits | 4 | Course Type | Experiment | |
| Target Year | 1st and 2nd year master's students | Target Student | ||
| Language | Japanese | Day/Period | ||
| Instructor name |
TAKASU KIYOSEI (Graduate School of Pharmaceutical Sciences Professor) TAKEMOTO YOSHIJI (Graduate School of Pharmaceutical Sciences Professor) Naka Hiroshi (Graduate School of Pharmaceutical Sciences Associate Professor) TAKIKAWA HIROSHI (Graduate School of Pharmaceutical Sciences Senior Lecturer) YAMAOKA YOUSUKE (Graduate School of Pharmaceutical Sciences Assistant Professor) NANJO TAKESHI (Graduate School of Pharmaceutical Sciences Assistant Professor) |
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| Outline and Purpose of the Course | In this course, students carry out research, including basic research on nanochemistry through catalytic asymmetric synthetic reactions and higher order structural control, development research on the practical synthesis and rational design of bioactive compounds and suspected biopolymers, basic research on drug development, and applied research on the physiological activity and biosynthesis of crude drugs and medical plants. Through laboratory experiments, students will learn how to approach research, how to review relevant literature, and how to draft research plans; they will also learn about specialist experimental techniques and data sorting and analytical methods, all the while developing comprehensive problem-solving skills. | |||
| Course Goals |
(1) To understand the details and objectives of specialized research on medical and organic chemistry. (2) To comply with research ethics and bioethics, and develop the ability to conduct experiments. (3) To learn how to search and research literature relating to specialized research and draft research plans, and to learn about specialized experiment techniques, data sorting, and analytical methods. (4) To develop the ability to keep working on research in order to solve issues related to specialized research. |
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| Schedule and Contents |
1-15: The following experiments will be conducted: ・Experiments related to the development of advanced molecular transformations, including bond formation reactions and annulation reactions ・Experiments related to asymmetric catalytic reactions ・Experiments related to catalytic reactions using transition metal catalysts ・Experiments related to the discovery of chiral artificial catalyst molecules ・Experiments related to the research of total synthesis in natural organic compounds ・Experiments related to the chemical synthesis of biopolymers, including peptides, proteins, glycans, and nucleic acids. ・Experiments related to the discussion of biofunctional molecules, such as enzyme inhibitors and receptor ligands ・Experiments related to diversity and secondary metabolic functional analysis of medicine plants ・Experiments related to the search for and evaluation of natural medical resources |
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| Evaluation Methods and Policy | Students will be evaluated based on class participation in terms of attitude and approach in day-to-day research, and will also be assessed on their research presentation and speech, and their presentation at the research report meeting. | |||
| Course Requirements | None | |||
| Study outside of Class (preparation and review) | Students should always be studying, thinking, and acting independently. | |||
| Textbooks | Textbooks/References | Not used | ||
| References, etc. | Others; will refer to scientific papers, review articles, and textbooks where appropriate. | |||
