Toxicological Sciences
| Numbering Code | P-PUB01 8H162 LB90 | Year/Term | 2022 ・ First semester | |
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| Number of Credits | 2 | Course Type | Lecture | |
| Target Year | Professional degree students | Target Student | ||
| Language | Japanese and English | Day/Period | Wed.4 | |
| Instructor name |
HARADA KOUJI (Graduate School of Medicine Associate Professor) OKUDA HIROKO (Graduate School of Medicine Program-Specific Associate Professor) FUJITANI TOMOKO (Part-time Lecturer) HARADA MARIKO (Part-time Lecturer) FUJII YUKIKO (Part-time Lecturer) |
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| Outline and Purpose of the Course |
I. Course Description The hazardous effects of chemicals on human health have been traditionally investigated in toxicology while therapeutic ones have been investigated in pharmacology. In this course, selected known episodes of environmental pollutions, metals and organic substances will be given. We will discuss the toxicities of common chemicals in our modern lives: mercury, dioxin, lead, thallium and cannabinoids. The aim of this course is to provide a scientific basis of modern toxicology. |
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| Course Goals |
II. Course Goals and Objectives Introduction to basic toxicology Knowledge for the toxic effects of some environmental pollutants, metals and organic substances familiar to us. Knowledge for developmental toxicology and carcinogenesis Analytical skill for toxicokinetics and toxicodynamics Skill for regulatory strategy to minimize the toxic effects of chemicals |
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| Schedule and Contents |
Course Schedule 1 Orientation 2 Alcohol toxicity and genetics 3 Beyond the 100th anniversary of Insulin- overview and toxicological issues 4 Neonicotinoid pesticide 5-6 Mercury poisonings 7-8 Arsenic poisonings 9 Opioid and cannabinoid 10 Cause of Chiredren's Death in India during summer 11 Aconitine 12 Phytoestrogens 13 Persistent organic pollutants 14-15 Group work |
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| Evaluation Methods and Policy | Attendance and active participation in the lecture 30%; Report assignment and presentation 70 % | |||
| Course Requirements | None | |||
| Study outside of Class (preparation and review) | Group discussion will be performed by students in Out-of-Class. | |||
| Textbooks | Textbooks/References | Handouts | ||
