Numbering Code	G-MED41 8S003 LE87	Year/Term	2022 ・ Second semester
Number of Credits	4	Course Type	lecture and seminar
Target Year	Doctoral students	Target Student
Language	English	Day/Period
Instructor name	MATSUDA FUMIHIKO (Graduate School of Medicine Professor) NAGASAKI MASAO (Center for the Promotion of Interdisciplinary Education and Research Program-Specific Professor) KAWAGUCHI SHUJI (Graduate School of Medicine Associate Professor)
Outline and Purpose of the Course	DNA sequencing technology is increasingy popularized, the application of this technology in the clinical medicine is now coming into reality. The aim of this course is to provide knowledges which are necessary to understand Genomic Medicine. In this Genomic Medicine II, which is the latter half of the Genomic Medicine course through the year, the link between basic science and clinical medicine will be focused, from the currently ongoing practice to future perspectives. A lecture is provided by expert researcher each week. Students are also required to particpate in the symposium of Kyoto Course on Bioinformatics for Genomic Medicine.
Course Goals	Understand the basic concepts behind Genomic Medicine Learn about current and upcoming application of genetic information in the clinical practice Learn about future perspectives of this field
Schedule and Contents	・Enhancer & Disease (Prof. Murakawa Yasuhiro) ・Genome, Disease and Artificial Intelligence(Assoc. Kawaguchi Shuji) ・High-Dimensional Statistical Methods: Challenges and Innovations (Institute of Epidemiology and Preventive Medicine, National Taiwan University) ・Genetics of diseases: Structural Variants & Quantitative traits(Prof. Masao Nagasaki) ・COVID-19(Prof. Masao Nagasaki) ・Genomic Database Resources for Rare Diseases (Prof. Masao Nagasaki) ・Genomics for Drug Discovery（Prof. Yukinori Okada） ・Pharmacogenomics (Prof. Taisei Mushiroda,Team leader, RIKEN Center for Integrative Medical Sciences) ・Pattern Discovery（Mario Foglio ） ・Destructive innovation of vaccine R&D during and after COVID-19（Prof.Ken Ishii,The University of Tokyo） ・Analysis for highly polymorphic regions(Assoc. Kawaguchi Shuji) ・A condensed overview of methods in Infectious Disease Public Health（Dr.PAUL, Richard,Institut Pasteur, Unit of Functional Genetics of Infectious Diseases）　　　　　　　　　　　　　　　　　　 （to be determined）
Evaluation Methods and Policy	Evaluated by submission assignments.
Course Requirements	Student needs to have will to make use of genomics and other omics information into clinical medicine in the future.
Study outside of Class (preparation and review)	NA
Textbooks	Textbooks/References	Informed in class.