Genetic Medicine, Ethics and Society
| Numbering Code | P-PUB01 8N015 LJ90 | Year/Term | 2022 ・ First semester | |
|---|---|---|---|---|
| Number of Credits | 2 | Course Type | Lecture | |
| Target Year | Professional degree students | Target Student | ||
| Language | Japanese | Day/Period | ||
| Instructor name | KOSUGI SHINJI (Graduate School of Medicine Professor) | |||
| Outline and Purpose of the Course |
[Basic information] Class date and time: 2nd period of Wednesdays (there may be exceptions) Classroom: Building G, 3rd Floor, Seminar room Level: Basic Staff in charge: Shinji Kosugi (subject coordinator), Takahito Wada, Ken Nakajima, Takahiro Yamada, Hideaki Sawai, Hidenori Kawasaki [Course overview] Ethical considerations are essential in genetic/advanced medicine. This course is focused on the basics of medical ethics, centered on genetic medicine. Understanding the different guidelines involved is of vital importance. It also outlines the current state of genetic medicine in Japan, including its social foundation. |
|||
| Course Goals | Understand the ethical guidelines for genetic medicine and medical science, as well as the basics of ethical issues in genetic testing in pediatrics/obstetrics, as well as in gynecology genetic medicine, and social infrastructure. | |||
| Schedule and Contents |
[1st lecture] 4/13 [Kosugi 1] General Theory of Genetic Medicine: The first compulsory subject of the genetic counselor course is a general introduction, not necessarily related to ethics. The peculiarities of ethical issues in genetic medicine, sharing genetic information, and the unintended disclosure of genetic information are also discussed. [2nd lecture] 4/20 (First Clinical Auditorium) [Kosugi 2] A look at various guidelines concerning genetic medicine. [3rd lecture] 4/27 [Kosugi 3] Ethical Guidelines (and Others) for Human Genome and Gene Analysis Research: Ethical issues involved in human gene analysis conducted as research, as well as the boundaries and distinctions between research and clinical practices. [4th lecture] 5/11 [Kosugi 4] Gene Analyses Conducted by Companies: The issues involved in outsourcing genetic tests to external entities such as clinical testing companies, as well as issues in gene tests carried out in non-medical institutions. [5th lecture] 5/18 [Kosugi 5] Guidelines for Genetic Testing and the Significance of Gene Testing: A look at ethical issues that must be considered when performing clinical genetic testing, as well as the meaning of gene diagnosis and its issues while clarifying the differences between probands and relatives. [6th lecture] 5/25 [Nakajima 1] About Pre-Symptomatic Gene Diagnosis: An analysis of the meaning of pre-symptomatic genetic diagnosis and susceptibility diagnosis and the issues involved, while clarifying the differences among neurodegenerative diseases and familial tumors. [7th lecture] 6/1 [Nakajima 2] Carrier Diagnosis: The meaning of carrier detection in autosomes, X-linked inheritance recessive hereditary diseases, and balanced chromosome translocation. [8th lecture] 6/8 [Wada 1] Diagnosis and Notification of Pediatric Hereditary Diseases and Guardianship: A look at ethical issues in childhood-onset hereditary diseases. [9th lecture] 6/8 5th period [Yamada1] Induced Abortion: Induced abortion in Japan and the ethical issues involved. [10th lecture] 6/15 [Yamada2] Prenatal Diagnosis and Assisted Reproductive Technology: A look at the ethical issues of prenatal diagnosis, and a detailed analysis of ethical questions surrounding assisted reproductive technologies due to infertility/infecundity. [11th lecture] 6/15 5th period [Wada 2] The Diversity of Bioethics: An analysis of various bioethics of patients and clients and how to deal with them. [12th lecture] 6/22 [Wada 3] Disabilities and Bioethics: A look at bioethics from the perspective of disabilities. [13th lecture] 6/29 5th period [Yamada 3] Handling Secondary Findings in Genome Medicine: Ethical issues when dealing with secondary findings different from the original purpose obtained, with the recent introduction of comprehensive genome analysis in clinical practice. [14th lecture] 6/29 4th period [Sawai] Policies to Counter Declining Fertility (Healthy Parents and Children 21): Various measures have been implemented to counter the falling birthrate, which slows society’s growth. Some of these measures produced results, while others did not. This lecture looks at what went wrong. [15th lecture] 6/30 [Kawasaki] Neonatal Care and Ethics: Ethical problems in neonatal care. 7/13 Final test Written test 8/3 Retest Written test |
|||
| Evaluation Methods and Policy | Comprehensive evaluation of tests, reports, active participation in classes, presentations, attendance, and other activities. | |||
| Course Requirements |
Compulsory subjects for first-year students in the Genetic Counselor Course Availability for students majoring in Human Health Sciences: Contact us in advance |
|||
| Study outside of Class (preparation and review) | Instructions will be given accordingly | |||
| Textbooks | Textbooks/References | Other materials will be distributed accordingly. | ||
