Experimental Course of Molecular Microbial Science1

Numbering Code G-AGR03 5CC41 EB79 Year/Term 2022 ・ Year-round
Number of Credits 6 Course Type Experiment
Target Year Target Student
Language Japanese Day/Period
Instructor name KURIHARA TATSUO (Institute for Chemical Research Professor)
KAWAMOTO JUN (Institute for Chemical Research Associate Professor)
TAKUYA OGAWA (Institute for Chemical Research Assistant Professor)
Outline and Purpose of the Course The object of this course is to let students acquire a deep knowledge of molecular microbial science and skills in performing scientific research by conducting research on a particular subject in the field of basic microbiology, applied microbiology, metabolic biochemistry, and enzyme biochemistry.
Course Goals Students will acquire a deep knowledge of molecular microbial science and skills in performing scientific research in this field.
Schedule and Contents Each student will be engaged in the research on the following topics.

1. Molecular basis of the environmental adaptation of extremophiles and their application
Molecular mechanism of the environmental adaptation of extremophilic microorganisms such as psychrotrophic bacteria is under investigation. Application of these microorganisms and their enzymes will be explored.

2. Structures, functions, and reaction mechanisms of microbial enzymes
Microorganisms are capable of converting a great variety of chemicals. They produce various unique enzymes to assimilate or degrade substrates in the environment. Many of these enzymes are attracting a great deal of attention because of their possible industrial applications. Structures, functions, and reaction mechanisms of microbial enzymes are under investigation, and their applications will be explored.

3. Functions of lipids and proteins in biological membranes
Biological membranes separate inside and outside of the cells. Various essential biological processes such as influx of nutrients, efflux of wastes, and signal transduction occur at the membrane. Biosynthesis of phospholipids and interaction between phospholipids and proteins are under investigation to understand how biological membranes are constructed and properly function. Biogenesis and application of extracellular membrane vesicles produced by bacteria are also under investigation.
Evaluation Methods and Policy Grading will be based on the attitude to the research and scientific achievements.
Refer to current year's 'Guide to Degree Programs' for attainment levels of evaluation.
Course Requirements Basic knowledge of biochemistry and microbiology is required.
Study outside of Class (preparation and review) Students will be asked to search for papers relevant to their own research in the field of molecular microbial science and read them.
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