Experimental Course of Biofunction Chemistry2
| Numbering Code | G-AGR03 6CC36 EJ79 | Year/Term | 2022 ・ Year-round |
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| Number of Credits | 6 | Course Type | Experiment |
| Target Year | Target Student | ||
| Language | Japanese | Day/Period | |
| Instructor name |
MIYOSHI HIDETO (Graduate School of Agriculture Professor) MURAI MASATOSHI (Graduate School of Agriculture Associate Professor) masuya takahiro (Graduate School of Agriculture Program-Specific Assistant Professor) |
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| Outline and Purpose of the Course | We will learn basic experimental techniques and attitude through the biorational design-syntheses, mode of action study, and structure-activity relationship of biologically active chemicals. | ||
| Course Goals | We will learn basic experimental techniques and attitude through the biorational design-syntheses, mode of action study, and structure-activity relationship of biologically active chemicals. | ||
| Schedule and Contents |
There are a variety of biologically active compounds which regulate the bioenergetic systems such as mitochondrial respiratory enzymes and transporters. This course addresses the design syntheses and the action mechanisms of such chemicals synthesized in our laboratory. In particular, we will focus a close relationship between organic chemistry and biology activity. Main synthetic targets will be: 1) Quinone derivatives 2) Cardiolipins (a unique phopspholipid) 3) Acetogenins and quinazoline, inhibitors of respiratyory complex I |
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| Evaluation Methods and Policy | Attitude to the research activity and scientific level of the research | ||
| Course Requirements | Organic chemistry and biochemistry | ||
| Study outside of Class (preparation and review) | Organic chemistry and biochemistry | ||
