Cellular Biochemistry

Numbering Code G-AGR03 6CA20 LJ79 Year/Term 2022 ・ Intensive, First semester
Number of Credits 1 Course Type Lecture
Target Year 2nd year master's students Target Student
Language Japanese Day/Period Intensive
Instructor name KIOKA NORIYUKI (Graduate School of Agriculture Professor)
KIMURA YASUHISA (Graduate School of Agriculture Associate Professor)
KURODA MITO (Graduate School of Agriculture Assistant Professor)
Outline and Purpose of the Course This course is to learn current concepts in Cellular Biochemistry.
Topics include cell adhesion to extracellular matrix, which regulates cell proliferation, survival, differentiation, migration, and mechanosensing/mechanotransduction through cell adhesion molecules, and ABC proteins, which are involved in protecting our health by transporting various xenobiotics and endogenous lipids.
Course Goals Students will understand the basic concepts underlying life phenomena and develop the ability to enhance their knowledge of animal cells independently.
Schedule and Contents The course will cover the following topics related to:
1) Cell adhesion and mechanosensing/mechanotransduction:
-Regulation of cell differentiation and migration by cell adhesion to extracellular matrix
-Sensors and transducers for stiffness of extracellular matrix
-Relationship between cell adhesion and cancer metastasis

2) ABC proteins:
-Structures and functions of transporters, ion channels, and receptors
-Relationships between ABC proteins and lifestyle diseases such as arteriosclerosis and cancer.

The course will be held from 1st to 6th periods on Monday and from 4th to 5th periods on Tuesday.
Evaluation Methods and Policy  Grading will be based on an overall assessment of attendance and the grade received on the report.
Refer to current year's 'Guide to Degree Programs' for attainment levels of evaluation.
Course Requirements None
Study outside of Class (preparation and review) Review and understand the course materials so that you can express what you have learned in class in your own words.
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