Numbering Code	U-AGR01 3A257 LJ69	Year/Term	2022 ・ Second semester
Number of Credits	2	Course Type	Lecture
Target Year	2nd year students	Target Student
Language	Japanese	Day/Period	Thu.1
Instructor name	YOSHIDA KENTARO (Graduate School of Agriculture Professor)
Outline and Purpose of the Course	Heredity is a universal principle of living things. Genetic information, which is the blueprint of life, is passed down from parent to child and from child to grandchild. The discipline of genetics covers the transmission and function of genetic information, mutations and the mechanism of gene expression. Basic knowledge of genetics is essential for those who advance to life science-related fields in the future. In this course, you will learn the basics of classical genetics, molecular genetics, and genomics.
Course Goals	To acquire the basic knowledge of genetics and genomics that is necessary to read and understand specialized books, original papers, and reviews. Understand and master the development and thinking of genetic logic by virtually re-experiencing genetic discoveries from classical experiments.
Schedule and Contents	The lectures will proceed according to the following lesson plan. One lecture will be allocated to each chapter of the textbook Essential Genetics: Genome Science, but the order and number of lectures might change depending on the course progress. Lecture 1: Genetics of horizontal gene transfer Lecture 2: Chromosome basis of heredity Lecture 3: Gene linkage and gene mapping Lecture 4: Chromosome behavior Lecture 5: DNA structure, replication, and its manipulation Lecture 6: Bacterial and bacteriophage genetics Lecture 7: Molecular genetics of gene expression Lecture 8: Molecular mechanism of gene regulation Lecture 9: Genomics, proteomics, and genetic engineering Lecture 10: Genetic regulation of development Lecture 11: Molecular mechanisms of mutations and DNA repair Lecture 12: Cell cycle and molecular genetics of cancer Lecture 13: Molecular evolution and population genetics Lecture 14: Genetic basis of complex traits [Final exam] Lecture 15: Feedback One or two topics from the chapter will be chosen and explained. Data and findings from original papers might be introduced to explain the research.
Evaluation Methods and Policy	Evaluation method: Participation in assignments (40%) and final exams (not open book) (60%). The evaluation criteria and policies are based on the evaluation criteria and policies described in the Student Handbook of the Faculty of Agriculture for the relevant academic year.
Course Requirements	None in particular
Study outside of Class (preparation and review)	Original papers and books related to the learning content will be shown during the lecture. Please deepen your understanding by referring to the original papers. Chapter 1 will be finished in 90 minutes. Self-study is essential to understanding the content of the chapter. Assignments will be given for each lecture.
Textbooks	Textbooks/References	Daniel L. Hartl, Essential Genetics: A Genomics Perspective (7th Edition). Burlington: Jones & Bartlett Learning, 2020. ISBN: 978-1284152456
References, etc.	William S. Klug, Michael Cummings, Michael A. Palladino, Charlotte A. Spencer, and Darrell Killian, Concepts of Genetics (12th edition), Pearson, 2018. ISBN:9780134604718. Written in plain Englishwith easy-to-understand figures. A textbook at the same level as essential genetics.