Numbering Code	U-AGR06 2F116 LJ79	Year/Term	2022 ・ Second semester
Number of Credits	2	Course Type	Lecture
Target Year	2nd year students	Target Student
Language	Japanese	Day/Period	Wed.1
Instructor name	YASUKAWA KIYOSHI (Graduate School of Agriculture Professor) TAKITA TEISUKE (Graduate School of Agriculture Assistant Professor)
Outline and Purpose of the Course	Enzymes are catalysts with high selectivity and efficiency. To understand enzymes from a chemical viewpoint, reaction kinetics, activity control, reaction mechanism, etc. are outlined.
Course Goals	It provides a systematic understanding of the kinetics and mechanisms of enzymes. Enzyme responses can now be considered at the molecular level.
Schedule and Contents	Lectures on the following topics are planned. First session: Classification of enzymes Second session: Chemical kinetics Third session: Steady-state reaction kinetics Fourth session: Michaelis-Menten equation and rate parameters Fifth session: Inhibition Sixth session: Effects of temperature Seventh session: Effects of pH Eighth session: Allosteric enzymes Ninth session: Response mechanisms Tenth session: Coenzymes Eleventh session: Steady-state reaction kinetics of multi-substrate enzymes Twelfth session: Pre-steady state reaction kinetics Thirteenth session: Transition phase kinetics Fourteenth session: True enzyme reaction analysis Fifteenth session: Feedback (undecided)
Evaluation Methods and Policy	[Evaluation method] Quiz totals (out of 20 points) from the first to tenth sessions, and the score (out of 80 points) on the final test will be evaluated as a total of 100 points. [Evaluation policy] Evaluation standards and policies are based on those described in the Faculty of Agriculture Handbook for the relevant year.
Course Requirements	It is desirable to have basic knowledge of biochemistry, organic chemistry, and physical chemistry.
Study outside of Class (preparation and review)	Preparation: It is desirable to read textbooks in advance. Review: Read the textbooks, and take quizzes and class notes.
Textbooks	Textbooks/References	L. A. A. Moran, H. R. Horton, K. G. Scrimgeour, M. D. Perry ホートン 生化学 第５版 (Tokyo Kagaku Dojin) ISBN: 978-4-8079-672-7
References, etc.	T. D. H. Bugg (Translated by Kuniyo Inoue) "入門 酵素と補酵素の化学" (Springer-Verlag Tokyo) ISBN: 978-4431711926