Numbering Code	U-AGR02 2B112 LJ79	Year/Term	2022 ・ First semester
Number of Credits	2	Course Type	Lecture
Target Year	2nd year students	Target Student
Language	Japanese	Day/Period	Mon.1
Instructor name	YURIMOTO HIROYA (Graduate School of Agriculture Associate Professor) KISHINO SHIGENOBU (Graduate School of Agriculture Associate Professor)
Outline and Purpose of the Course	This course aims to provide an understanding of the basic mechanisms of precise and minute natural life phenomena at the molecular level, based on a knowledge of chemistry. Enzymes that catalyze reactions in living organisms and basic metabolic pathways (sugars, lipids, energy) are explained from the chemical and physiological viewpoints.
Course Goals	To deepen our understanding of not only various reactions in a living body but also the properties of enzymes used in various industries such as production of useful substances and diagnostic agents, as well as their reactions. Additionally, regarding the basic metabolism common to many organisms, to understand the flow of compounds and enzymatic reactions involved in the degradation and biosynthetic pathways of sugars and lipids, as well as understand the physiological significance of each pathway and individual reactions. Furthermore, to understand how energy generated in the decomposition process is used for ATP synthesis.
Schedule and Contents	Lectures will be on the following topics, and each will be covered for the number of weeks mentioned in brackets depending on the level of understanding of the students. The order of lectures for each item/sub-item is not fixed and will be decided by the course in-charge depending his lesson plans and the students' background and level of understanding. Instructions will be given whenever required on how to proceed with the 15 lectures, and students are required to come sufficiently prepared. 1. Enzymes (Kishino) [2 weeks] 2. Glycolysis pathway (Kishino) [2 weeks] 3. Alternative pathways of sugar metabolism and fermentation (Kishino & Yurimoto) [2 weeks] 4. Citric acid cycle (Kishino) [2 weeks] 5. Electron transport chain and oxidative phosphorylation (Yurimoto) [3 weeks] 6. Lipid metabolism (Yurimoto) [3 weeks] Final examination Feedback [1 week]: We lecturers will be available in the laboratory or classroom to answer students' questions.
Evaluation Methods and Policy	[Evaluation method] Evaluation will be conducted based on class performance (15 marks) and final examination (85 marks). [Evaluation criteria] The evaluation criteria and policies are in accordance with the "Evaluation Criteria and Policies" described in the Student Handbook of the Faculty of Agriculture for the relevant year.
Course Requirements	It is desirable, but not compulsory, to take the Introduction to Applied Life Science III (B105) course for background.
Study outside of Class (preparation and review)	Review what was covered in each lecture.
Textbooks	Textbooks/References	基礎生化学, ヴォート, (東京化学同人), ISBN:9784807909254, Either of the 4th or 5th edition
References, etc.	生化学第４版(上), ヴォート, (東京化学同人), ISBN:9784807908073 生化学第４版(下), ヴォート, (東京化学同人), ISBN:9784807908080