Today, expectations for interdisciplinary research in the relationship between science, technology and innovation are increasing, as the need for the humanities and social sciences explicitly referenced in the 6th Science, Technology and Innovation Basic Plan. This is due to the fact that humanity has the responsibility to solve global issues such as energy, climate change, and poverty etc., and to build a society that can coexist sustainably. Now, we need to change drastically the approach to innovation. Well-being is an essential element for such sustainable coexistence, and the pursuit of appropriate technologies that can promote the sharing of well-being among more people is a challenge for humanity. In this symposium, representative speakers from the Graduate School of Engineering, Kyoto University and the Center for the Promotion of Interdisciplinary Education and Research will be invited to cross-talk about innovation that support well-being with our GSAIS speakers.