Introduction to Immunology-E2

Numbering Code U-LAS14 20072 LE68 Year/Term 2021 ・ Second semester
Number of Credits 2 Course Type Lecture
Target Year Mainly 1st & 2nd year students Target Student For all majors
Language English Day/Period Thu.3
Instructor name KIM MINSOO (Graduate School of Medicine Associate Professor)
Outline and Purpose of the Course Our body is constantly exposed to foreign microbes, many of which cause infectious diseases. However, our body has an intricate immune system that defends against such infections. Understanding this host immune system gives us greater insights into human diseases and enables us to develop novel therapeutic tools. This course, therefore, focuses on the immune system at the molecular, cellular, and whole-organism levels. Topics include: cells and tissues of the immune system, lymphocyte development, structure and function of antigens and antibodies, cell biology of antigen processing and presentation, pathogenesis of immunologically-mediated diseases, and disease control. The first four lectures provide a simple introduction to immunology, and subsequent lectures focus on specialized topics that will give a detailed understanding of the immune system.
Course Goals To understand the basic concepts of immune cells and organs.
To understand how our body responds to foreign antigens and self-derived threats.
To become familiar with various research topics in immunology.
Schedule and Contents 1. Introduction to immunology: the body’s defense
2. Elements of the immune system and their roles in defense
3. Introduction to innate immunity: the first lines of defense
4. Overview of adaptive immunity
5. Cells and tissues of the immune system
6. Antibodies and antigens
7. Antigen presentation by T lymphocytes
8. Recognition of self and non-self by the innate immune system
9. Cellular components of the innate immune system
10. B cell development and antibody mediated immunity
11. T cell development and cell-mediated immunity
12. Failures of the body’s defenses
13. Disorders in the immune system
14. Immunological memory and vaccination
15. Final examination
16. Feedback
Evaluation Methods and Policy Evaluation will be based on class attendance and participation (30%), homework (20%), and Final exam (50%).
Course Requirements The course is open to all students, although a background in cell biology is highly recommended.
Study outside of Class (preparation and review) To achieve the course goals, students should read the recommended textbooks before the class and review the course handouts.
Textbooks Textbooks/References Cellular and Molecular immunology, Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai, (Elsevier), ISBN:978-0323479783
Janeway’s Immunology, Kenneth Murphy, Casey Weaver, (Garland Science), ISBN:978-0815344452
Molecular Biology of the Cell, Bruce Alberts et al., (Garland Science), ISBN:978-0815344643
References, etc. Introduced during class