Introduction to Biochemistry-E2

Numbering Code U-LAS14 20037 LE68 Year/Term 2021 ・ Second semester
Number of Credits 2 Course Type Lecture
Target Year Mainly 1st & 2nd year students Target Student For science students
Language English Day/Period Tue.3
Instructor name Shohab YOUSSEFIAN (Graduate School of Medicine Professor)
Outline and Purpose of the Course This introductory course focuses on the basic concepts of biochemistry. It begins from the molecular design of life and considers its major players; nucleic acids as the genetic material, and then proteins, enzymes, carbohydrates, lipids and cell membranes. Based on these preliminary concepts, the course then continues to consider the basic processes involved in metabolism and energy generation in living organisms.
Course Goals To appreciate that by understanding some of the underlying concepts and principles of the molecular and biochemical processes that control life, we can more easily understand the complexities of diverse biological and physiological systems.
Schedule and Contents Main Topics:
1. Introduction to biochemistry, an evolving science
2. Genomes, DNA and DNA replication
3. Genes and gene expression
4. Protein composition and structure
5. Exploring DNA and genes
6. Exploring proteins
7. Introduction to enzymes
8. Carbohydrates
9. Lipids and cell membranes
10. Introduction to metabolism
11. Glycolysis
12. Citric acid cycle
13. Oxidative phosphorylation
14. Final examination
15. Feedback discussions

Please note that these 13 lecture subjects will cover the complete 14 lecture course of the series.
Evaluation Methods and Policy Evaluation will be based on class attendance and active participation (~25 %), quizzes (~30 %), other assignments (5 %), and a final assignment/examination (~40 %).
Course Requirements None
Study outside of Class (preparation and review) Whether these lectures are presented as face-to-face classes or, because of COVID-19, as online classes, the general structure and format will the same form of FLIP lectures. Here, on-demand videos and handouts for each lecture will be uploaded on PandA one week before each class so that students have time to go through them carefully. These videos will include full explanations of the materials as well as other visual tools such as animations and videos that will help better explain the concepts. Then, during each weekly face-to-face (or on-line) class, we will discuss the concepts presented in the videos, with each student explaining their answers to various thought-provoking questions, thereby developing deeper insights into the materials. On-line forums will be opened after the class to allow students to discuss areas that are still unclear or to upload videos that better explain certain issues. Quizzes throughout the semester will challenge the understanding and learning of the various concepts.
Textbooks Textbooks/References Biochemistry 7th edition, International 2012, Berg, Tymoczko and Stryer, (W. H. Freeman and Co. ), ISBN:978-1-4292-7635-1, A few newer versions are available in the Medical School Library