Seminar in Basic Patho-Functional Analysis
| Numbering Code | G-PHA01 72308 SJ86 | Year/Term | 2022 ・ Irregular, year-round | |
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| Number of Credits | 2 | Course Type | Seminar | |
| Target Year | 1st and 2nd year master's students | Target Student | ||
| Language | Japanese | Day/Period | ||
| Instructor name |
ONO MASAHIRO (Graduate School of Pharmaceutical Sciences Professor) TAKAKURA YOSHINOBU (Graduate School of Pharmaceutical Sciences Professor) KANEKO SHIYUUJI (Graduate School of Pharmaceutical Sciences Professor) TAKAHASHI YUUKI (Graduate School of Pharmaceutical Sciences Associate Professor) SHIRAKAWA HISASHI (Graduate School of Pharmaceutical Sciences Associate Professor) Hiroyuki Watanabe (Graduate School of Pharmaceutical Sciences Senior Lecturer) |
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| Outline and Purpose of the Course |
(Aim) Through presentations and accompanying discussions, this course aims to equip student with knowledge relating to biofunctional analysis, molecular imaging, pharmacokinetics, drug delivery systems, central and peripheral pharmacology, and the functional analysis of membrane transport proteins. They will also learn basic approaches in the interpretation of individual data and logicality, and develop problem-solving skills to move forward with research and deal with various scientific problems. (Summary) The course will introduce the latest literature on the functional analysis of membrane transport proteins and drug efficacy evaluations, including molecular pharmacology, in vivo image analysis, molecular imaging, the in vivo kinetics and delivery technologies of gene therapy pharmaceuticals, ion channels, and transporters. |
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| Course Goals |
・To gain knowledge about the latest findings needed to conduct research in the fields of patho-functional bioanalysis and biopharmaceutical sciences, and drug metabolisms. ・Develop the presentation and communication skills needed to excel as a researcher. |
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| Schedule and Contents |
1-15: The following seminars will be held. ・Introduction and data analysis of research on the state analysis of biological functions ・Introduction and data analysis of research on the molecular design of biomolecular imaging probes ・Introduction and data analysis of research on pathophysiology and pathogenesis through biomolecular imaging ・Introduction and data analysis of research on the application of biomolecular imaging in drug development ・Introduction and data analysis of research on the molecular imaging of brain and cardiac functions, tumors, etc. ・Introduction and data analysis of research on the discovery of clinical diagnostic imaging agents and radioactive therapeutic agents ・Introduction and data analysis of research on bioinorganic chemistry ・Introduction and data analysis of research on the in vivo kinetics of nucleic acid drugs and the dominant factors of intracellular dynamics ・Introduction and data analysis of research on the optimization of gene therapy and DNA vaccines ・Introduction and data analysis of research on the uptake mechanisms of macromolecular drugs in macrophage and dendritic cells ・Introduction and data analysis of research on gene function analysis using RNA interference and its therapeutical applications ・Introduction and data analysis of research on drug delivery based on nucleic acids ・Introduction and data analysis of research on targeting medicament carriers ・Introduction and data analysis of research on statistical analysis of the in vivo kinetics of macromolecular pharmaceuticals ・Introduction and data analysis of research on drug discovery, focused on membrane transport proteins ・Introduction and data analysis of research on the physical basis of pain and the action mechanisms of analgesics ・Introduction and data analysis of research on the molecular mechanisms of neuroplasticity and function change in drug addiction ・Introduction and data analysis of research on the activation mechanisms in glial cells ・Introduction and data analysis of the pathophysiology and pathogenesis of cerebrovascular disease ・Supplementary class and discussion |
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| Evaluation Methods and Policy | Students will be comprehensively evaluated based on seminar attendance and input in presentations and discussions. | |||
| Course Requirements | None | |||
| Study outside of Class (preparation and review) | Students should study and prepare for class by using the Internet to learn about the fundamentals of each seminar theme in advance. | |||
| Textbooks | Textbooks/References | Others; printouts will be distributed. | ||
| References, etc. | Others; may be specified according to seminar content. | |||
