Life Science: From Basics to Applications, from Molecular Biology to Systems Biology

Numbering Code G-BIO11 51026 LE68 Year/Term 2022 ・ Intensive, First semester
Number of Credits 1 Course Type Lecture
Target Year Master's students Target Student
Language English Day/Period Intensive
Instructor name HEJNA, James (Graduate School of Biostudies Specially Appointed Professor)
NAGAO MASAYA (Graduate School of Biostudies Professor)
IKURA TSUYOSHI (Graduate School of Biostudies Associate Professor)
KAMBE TAIHO (Graduate School of Biostudies Associate Professor)
IMAMURA HIROMI (Graduate School of Biostudies Associate Professor)
CARLTON, Peter (Graduate School of Biostudies Associate Professor)
KUMETA MASAHIRO (Graduate School of Biostudies Assistant Professor)
KATOH TOSHIHIKO (Graduate School of Biostudies Assistant Professor)
Outline and Purpose of the Course This class will be conducted entirely in English, and is designed to acquaint students with a broad range of research areas and methodologies, while encouraging students to consider the adaptability or combination of methods in other systems. Topics will range from a quick review of current molecular biology techniques, to presentations on signal transduction, regulation and epigenetics,energy metabolism,chromosome dynamics in meiosis,
roles of essential micronutrients, subcellular molecular dynamics, glycobiology, and others. Discussion is also encouraged. The class is primarily for first-year Master's students, but 2nd year Master's students may also enroll.
Course Goals Students will be exposed to a wide range of stimulating, current areas of research. One goal is to encourage students to become wide science readers, who can take an interdisciplinary approach to their research.
Students are expected to find something in a lecture that will in turn stimulate them to explore a subject more deeply on their own, or based on the optional reading lists provided by the lecturers.
Thus, they should spend an additional 2-3 hours per week doing their own reading.
Schedule and Contents Tentative Lecture Schedule is the following:
April 26,2022 Cloning techniques and expression systems
May 10, 2022 Basic Aspects of Erythropoietin
May 17, 2022 Studies of Histone Dynamics and DNA Metabolism
May 24, 2022 Studies of Essential Micronutrients
May 31, 2022 Studies of Energy Metabolism
June 7, 2022 Chromosome Dynamics in Meiosis
June 14 2022 Molecular Dynamics of subcellular environments
June 21, 2022 Basic Glycobiology

Note, lecture topics and schedule may be subject to change.
Evaluation Methods and Policy Grading will be based primarily on attendance and participation. Up to 2 missed classes with valid excuses can be made up by a short written assignment.
Further details will be announced in the first lecture.
Course Requirements Students should have a good undergraduate foundation in molecular and cellular biology.
Study outside of Class (preparation and review) Handouts will be provided to accompany the lectures, posted on PandA. Students can review these and also engage in optional outside reading in subjects that interest them. This may take 2-3 hours per week.If classes will be online, supporting literature and notes will be posted on PandA.
Textbooks Textbooks/References None required. M1 Students in particular should be learning about the general principles behind techniques on their own.
References, etc. Optional. Alberts et al. The Molecular Biology of the Cell, 6th Ed.
For students especially interested in Glycobiology, there is an optional textbook: Essentials of Glycobiology, available free on the NCBI Bookshelf: