Cancer Biology

Numbering Code G-BIO11 51022 LE68 Year/Term 2022 ・ Second semester
Number of Credits 2 Course Type Lecture
Target Year Master's students Target Student
Language English Day/Period Wed.2
Instructor name YOSHIMURA SHIGEHIRO (Graduate School of Biostudies Associate Professor)
HARADA HIROSHI (Graduate School of Biostudies Professor)
KAKIZUKA AKIRA (Graduate School of Biostudies Professor)
KUMETA MASAHIRO (Graduate School of Biostudies Assistant Professor)
Outline and Purpose of the Course This course is an intermediate-to-advanced course to study a wide variety of recent topics on cancer biology. Lectures will be given by researchers working in different fields in Kyoto, Tsukuba, and National Taiwan Universities through a long-distance learning system.
* This lecture will be conducted in English.
* Lecture hours are from 10:00 to 12:00, Wednesday.
Course Goals It is not "easy" for normal cells to become a cancer. During the transformation, cells alter a variety of cellular activities by modulating signaling pathways, genome controls, environmental responses, and so on. Students will learn 1) what is cancer, 2) how the cells acquire abilities to be cancer, 3) what is happening in cancer cells and tissues, 4) how can we study cancer, and 5) how can we detect, monitor and treat cancer.
Schedule and Contents This course starts in October, every Wednesday 10:00-12:00.
Handouts will be distributed online (PandA). Students are expected to prepare them by themselves. (Details will be announced at the first lecture.)
(1) Course Introduction: Kyoto U, National Taiwan U and U of Tsukuba,
(2) Introduction to Cancer Biology
(3-8) Cancer Genomics (genomics, epigenetics, Genome instability, Telomere biology, RNA regulation)
(9-14) Cancer Cell Biology (Tumor microenvironment, Tumor virology, Tumor growth, Signal transduction, Animal models)
(15) Feedback
Evaluation Methods and Policy Grading is based on attendance.
Course Requirements None
Study outside of Class (preparation and review) Recent papers related to the lecture topics will be assigned beforehand by the lecturers. Students are expected to read through the paper along with the lecture materials and prepare for discussion.
References, etc. Reference books will be suggested in the class