Exercises in Basic Organic Chemistry

Numbering Code U-ENG27 27103 LJ60 Year/Term 2021 ・ First semester
Number of Credits 2 Course Type Lecture
Target Year Target Student
Language Japanese Day/Period Mon.1
Instructor name YAMAGO SHIGERU (Institute for Chemical Research Professor)
KAYAHARA EIICHI (Institute for Chemical Research Assistant Professor)
Outline and Purpose of the Course This course systematically studies the basic concepts and principles of organic chemistry through lectures and exercises. Particular attentions are focused on the chemistry of carbonyl group, which is one of the most important functional group in organic chemistry. The organic chemistry of amines and heterocyclic compounds are also studied.
Course Goals Acquire the basic concept and knowledge, especially physical properties and reactions, of organic chemistry of carbonyl compounds, amines, and heterocycles.
Schedule and Contents 1. Aldehydes and ketones (2)
Study on the structures, properties, syntheses, and reactions of aldehydes and ketone.

2. Nucleophilic addition reactions (3)
Study on the reactions and reaction mechanisms of the nucleophilic addition reactions to aldehydes and ketones.

3. Carboxylic acids and nitriles (1)
Study on the structure, properties, syntheses, and reactions of carboxylic acids and nitriles

4. Carboxylic acid derivatives (2)
Study on the structure, properties, syntheses, and reactions of carboxylic acid derivatives, such as esters and acid halides.

5. Nucleophilic acyl substitution reactions (2)
Study on the reactions and reaction mechanisms of the nucleophilic acyl substitution reactions of carboxylic acid derivatives.

6. alpha-Substitution and condensation reactions of carbonyl group (2)
Study on the reactions and reaction mechanisms involving enolate anions of ketons and esters, such as alkylations and aldol reactions.

7. Amines and heterocycles (2)
Study on the structure, properties, syntheses, and reactions of amines and heterocycles.

8. Feedback (1)
Evaluation Methods and Policy Evaluate based on a final written examination and exercises and tests during the lecture.
Course Requirements Desirable to take Basic Organic Chemistry A and B.
Study outside of Class (preparation and review) Preparation and reviewing the textbook are needed.
Textbooks Textbooks/References 有機化学 生体反応へのアプローチ, マクマリー, (東京化学同人), ISBN:9784807906918
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