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You are here: Home en Syllabuses (2020) Graduate School of Engineering Chemistry & Chemical Engineering Supramolecular Chemistry

Supramolecular Chemistry


Numbering Code
  • G-ENG16 6D837 LJ61
  • G-ENG15 6D837 LJ61
Term 2020/Second semester
Number of Credits 2 credits
Course Type Lecture
Target Student Graduate
Language English
Day/Period Tue.4
  • Graduate School of Engineering, Associate Professor Juha Lintuluoto
  • Graduate School of Engineering, Senior Lecturer LANDENBERGER, Kira Beth
Outline and Purpose of the Course This course is open to all master and doctoral engineering students. The aim is to enhance students’ knowledge of non-covalent molecular interactions found in both synthetic and natural chemical compounds and materials. Additionally, students learn how to choose methods to study and observe non-covalent molecular interactions, and how to measure and evaluate them quantitatively. Throughout the course feedback will be given by instructors. The course will also improve students to gain confidence in studying English of supramolecular topics. The course contents are suitable for a wide variety of chemistry students.

Course Goals Understanding the nature and types of supramolecular interactions, and applying them into various chemical, biological and other materials applications.  
Schedule and Contents 1.Course Introduction & Interactions and methods in Supramolecular Chemistry: Non covalent interactions (H-bonding, pi-pi;lone-pairs and metals, ionic), spectrometric methods (NMR, UV-vis, Fluorescence, CD, Mass) Oct.6

2.Binding Constants, Cooperativity, Complementarity, Preorganization Equilibrium systems, enthalpy and entropy upon binding, quantitative analysis Oct.13

3.Cation Binding with Current Examples Cation binding, binding into anionic host molecules and neutral host molecules Oct.20

4.Anion Binding with Current Examples Anion binding, binding into cationic host molecules, and neutral host molecules Oct.27

5.Neutral molecule binding and Self-Assembly with Current Examples Neutral molecule binding into neutral or charged host molecules, self-binding molecules Nov.10

6.Supramolecular Devices, Sensors and Catalysis with Current Examples Electron transfer, energy transfer, information transfer in supramolecules Nov.17

7. Microcalorimetry Isothermal titration calorimetry to analyze binding thermodynamics of biomolecules.
Differential scanning calorimetry to analyze folding thermodynamics of proteins. Nov.24* Lecturer Prof. Oda, Kyoto Prefectural University

8. Crystal Engineering I Crystal engineering, crystal classes, crystal nucleation and growth, commonly found intermolecular interactions Dec.1

9. Crystal Engineering II Polymorphism, hydrates and solvates, cocrystals, crystal structure prediction Dec.8

10. Network Solids Zeolites, intercalates, coordination polymers (e.g. MOFs or COFs) Dec.15

11. Solid State Inclusion Compounds I Clathrates (structures and applications), catenanes, rotaxanes cyclodextrins Dec.22

12. Supramolecular Liquid Crystals Nature and structure of liquid crystals, applications and design, polymeric liquid crystals Jan.5* Lecturer Dr. Gabriel Toma, Osaka University

13. Solid State Inclusion Compounds II Helicates and helical assemblies, molecular knots and beyond Jan.12

14.Supramolecular Polymers, Gels and Fibers Supramolecular polymer structure and design, properties, kinetics and reaction mechanics of supramolecular polymers, applications Jan.19
Grading Policy Evaluation: 20% participation (engaging the classes and activity), 80% reports.
*More than 3 unexcused absence can result in course failure.
Prerequisites Active engagement in lectures, which provide basis for the reports required in this course. Each student is required to submit 4 chosen reports on any given topics during the course. However, 2 reports each should be submitted for the given topics on lectures 1-6 and 8-14, excluding lecture 12.

If you have any concerns or questions regarding the course, please do not hesitate to contact (075)- 383-7065 or landenberger.kirabeth.2x at or (075)-383-2876 or lintuluoto.juhamikael.7u at .

Preparation and Review Students should fulfill the report tasks out of class time (home work).